Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1 mg/kg BW (0.454 mg/lb) for 5 consecutive days. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. Safe-Guard AquaSol was administered orally in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. The margin of safety in broiler chickens was conducted in 480 broiler chickens. Chickens: Two margin of safety studies (growing broiler chickens and laying hens at peak egg production) and one reproductive safety study (broiler breeder chickens) were conducted. At the end of the treatment phase, gross necropsies were performed on 48 chickens from each group, and organs weights were evaluated. 2023 Best Veterinary Solutions, Inc.All Rights Reserved. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 6) Add the 1 to 1 dilution of Safe-Guard AquaSol in water to the water supply system as described below. Swine: Safe-Guard AquaSol must be administered orally to swine via the drinking water at a daily dose of 2.2 mg/kg BW (1 mg/lb) for 3 consecutive days. I happen to have a 10 ml pipet and a 100 ml volumetric flask as well as 1 ml and 3 ml syringes so it's rather simple for me to do the dilutions. Toss eggs for 14 days after last dose, a total of 19 days. Chickens: Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens and for the treatment and control of adult A. galli and Heterakis gallinarum in breeding chickens and laying hens. The average percent of medicated water consumed was 98.18%, thus the study demonstrated that 20% Fenbendazole Suspension has acceptable palatability. As an Amazon Associate, this site earns from qualifying purchases. In all chickens, feed and water intake, body weights, clinical health, and mortality were recorded. Deworming and treatment are important to ensure and maintain the health of your chickens and prevent the emergence of intestinal parasites. A common protocol was implemented in two different geographical locations and with two different investigators. However, its important to follow the specified instructions on the product label and consult your veterinarian for further assistance before using it on your chickens. In all chickens, feed and water intake, body weights, clinical health, and mortality were recorded. if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[300,250],'farmandchill_com-leader-2','ezslot_16',106,'0','0'])};__ez_fad_position('div-gpt-ad-farmandchill_com-leader-2-0'); According toMerck Animal Health, the manufacturer of Safe-Guard Aquasol, there is no egg withdrawal period required when using the product as a treatment for chickens. The daily dose of 2.2 mg fenbendazole per kg BW (1 mg/lb) which is equivalent to 0.011mL Safe-Guard AquaSol per kg BW (0.0045 mL/lb).The required daily volume of product is calculated from the total estimated body weight [kg] of the entire group of pigs to be treated. 2) Select a measuring device capable of accurately measuring a volume of at least twice the calculated Safe-Guard AquaSol daily volume. Safeguard is usually administered orally, I do it with an oral syringe. Smaller particle size helps prevent sedimentation and clogged pipes, filters or nipple drinkers. Emergencies / Diseases / Injuries and Cures, https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/3083, https://www.backyardchickens.com/threads/safeguard-mash-zero-day-egg-withdrawal.1254653/, Question on Safe-Guard vs Aquasol product info. A decrease of effectiveness over time may indicate the development of resistance to the dewormer administered. Innovative manufacturing process enables easy, effective deworming for broilers, breeders, pullets and laying hens through oral administration via drinking water. Use the medicated water within 24 hours. The medicated water must be prepared daily prior to each administration. In the study, the efficacy against adult A. galli was 99.4%. The efficacy against adult A. galli was 100%. The percent reduction in T. suis worm counts in the FBZ medicated animals was greater than 90% (98.5% in MN and 98.6% in CA) compared to the non-medicated animals using transformed data (geometric means). When Should I Check My Chickens for Worms? HOW SUPPLIED: 1 Liter and 1 Gallon (3,785 mL) HDPE plastic containers. Formulated in France. Safeguard is usually administered orally, I do it with an oral syringe. ORDER STATUS. The aquasol is formulated to be mixed in water, so it will stay suspended correctly. Swine: A multi-site, masked, negative-controlled dose confirmation field study was conducted to provide substantial evidence of the effectiveness of Fenbendazole (FBZ) Suspension (20% w/v) administered orally in drinking water to pigs for three consecutive days to provide a dose of 2.2 mg FBZ/kg body weight daily against the dose-limiting worm Trichuris suis (T. suis). For one-day fenbendazole treatments, dissolve 1 ounce of the fenbendazole product (Safe-Guard Aquasol or Panacur) in 1 cup of water for every 15 to 20 pounds of feed. Each study site selected pigs from one source herd verified to be free of T. suis infection. In this case, you would have to deworm your older chickens first before deworming the baby chicks. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. | Beginners Guide to High-Quality Meat. Formulated in France. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the medication tank containing the volume of drinking water usually consumed by the animals in 3 to 24 hours. Safe-Guard AquaSol should always be measured by adding it to a measuring device that already contains an equivalent volume of water.]. (fenbendazole oral suspension), For oral administration via drinking water. A fourth dose confirmation study was conducted in the United States (US) using 264 Rhode Island Red breed hens (12 months old). Please use the following formula: Follow the instructions in the order described below to prepare the medicated water. For Patent Information: http://www.merck.com/product/patent/home.html. Weaned, growing-finishing pigs of approximately 6 weeks of age were used in the study. [Note: If the total volume of the 1 to 1 dilution needed exceeds the volume of the largest available measuring device, divide the total volume into two or more smaller batches of 1 to 1 dilution, prepared following the steps below. Only two pigs at the Minnesota (MN) site that were treated with FBZ had abnormal post-treatment observations ("loose stools"). Be careful to avoid any accidental spill or loss of 1 to 1 dilution which may inadvertently result in less than the required dose of fenbendazole. Histopathologic evaluations were performed on the gross lesions collected during the necropsy. The average percent of medicated water consumed was 98.18%, thus the study demonstrated that 20% Fenbendazole Suspension has acceptable palatability. The margin of safety in laying hens was conducted in 144 laying hens. 99. The parameters evaluated in the study included feed and water intake, body weights, clinical health, egg production and weight, fertility, hatchability, and 14-day old chick viability. RESIDUE WARNING: Chickens: No withdrawal period is required when used according to labeling. 6) Add the 1 to 1 dilution of Safe-Guard AquaSol in water to the water supply system as described below. There were no abnormal observations made at the California (CA) site on pigs after FBZ administration. During treatment, all animals must have sole and unrestricted access to the medicated water. In all hens, feed and water intake, body weights, clinical health, mortality, egg production, and egg quality parameters (including egg shell thickness and strength, egg weight, and Haugh unit) were evaluated. A complete feed, adequate to meet the nutritional needs of the study animals, was offered to the animals in self-feeders throughout the study. Eggs that have worms will also potentially infect humans and cause illnesses. Prepare a 1 to 1 dilution (pre-dilution) of Safe-Guard AquaSol in water: 1) Calculate the volume of Safe-Guard AquaSol to be administered daily. Affiliate Disclosure Deworm as soon as you see the first symptoms of worm infestation among your chickens. Following the use of any dewormer, effectiveness of treatment should be monitored. Intestinal and Tracheal Parasites of Poultry, Use of Biosecurity and Natural Remedies for the Prevention of Poultry Disease in Natural and Organic Flocks. Copyright 1995-2023 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. Weaned, growing-finishing pigs of approximately 6 weeks of age were used in the study. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Chickens: Six pivotal dose confirmation studies and five field effectiveness studies were conducted to evaluate the effectiveness of Safe-Guard AquaSol oral suspension against adult A. galli in broiler chickens and replacement chickens and against A. galli and H.gallinarum in breeding chickens and laying hens. Swine: Animal safety was established using a combination of swine pharmacokinetic, physiologic, and pharmacologic data that provided a basis for bridging the safety data of Safe-Guard Type A medicated article (NADA 131-675) to Safe-Guard AquaSol oral suspension in swine. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. Copyright 2020 Intervet Inc., a subsidiary of Merck & Co., Inc., Madison, NJ 07940. In all three studies, the efficacy against A.galli (97.9%, 97.3%, and 93.9%) and H. gallinarum (99.8%, 96.9%, and 97.3%) was greater than 90%. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. 5) Fill up the measuring device containing the water with the calculated volume of the product to obtain the 1 to 1 dilution. At the end of the treatment phase, gross necropsies were performed on 12 hens from each group, and organs weights were evaluated. Fenbendazole is safe to use for chickens. The efficacy against adult A. galli was 90.2%. DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. The medicated water must be prepared daily prior to each administration. Fenbendazole (active ingred.) Safe-Guard Aquasol for Chickens & Swine Indications, Warnings and cautions for Safe-Guard Aquasol for Chickens & Swine, Direction and dosage information for Safe-Guard Aquasol for Chickens & Swine. Zyfend A, 30 mL. The daily dose is 2.2mg fenbendazole per kg BW (1 mg/lb) which is equivalent to 0.011mL Safe-Guard AquaSol per kg BW (0.0045 mL/lb).The required daily volume of product is calculated from the total estimated body weight [kg] of the entire group of pigs to be treated. . Stir the medicated water in the medication tank until the medicated water is visibly homogeneous. Swine: Animal safety was established using a combination of swine pharmacokinetic, physiologic, and pharmacologic data that provided a basis for bridging the safety data of Safe-Guard Type A medicated article (NADA 131-675) to Safe-Guard AquaSol oral suspension in swine. No withdrawal time is required for consumption of eggs or meat from treated birds when administered according to label directions. Keep out of reach of children. CATALOG QUICK ORDER. Another group of 120 chickens (60 male and 60 female) was provided non-medicated drinking water and used as a control group. Net volume 1 Liter, Set id: 62bd7997-81e5-46ca-806c-7407344449ae. Use within 6 months after opening. Swine: Safe-Guard AquaSol must be administered orally to swine via the drinking water at a daily dose of 2.2 mg/kg BW (1 mg/lb) for 3 consecutive days. After complete consumption of the medicated water, the chickens should have access to non-medicated drinking water ad libitum. Be careful to avoid any accidental spill or loss of 1 to 1 dilution which may inadvertently result in less than the required dose of fenbendazole. Consult your Veterinarian for assistance in the diagnosis, treatment, and control of parasitism. For a better experience, please enable JavaScript in your browser before proceeding. If you do not know what type of worms your flock has, that's something an avian vet can assist you with. At the end of the treatment phase, 30 breeding chickens (10 male and 20 female) from each group were necropsied; and gross pathology and weights of testes and female reproductive tracts were evaluated. The volume of water in the stock suspension container has to be calculated taking as a basis the present injection rate of the dosing pump and the volume of drinking water usually consumed by the animals over a period of 3 to 24 hours. Ensure that the total amount of medicated water offered is consumed. Do not freeze. Follow the instructions in the order described below to prepare the medicated water. In the study, the efficacy against adult A. galli was 99.4%. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Individual fecal samples were obtained from each candidate animal 46, 47, and 48 days after T. suis inoculation and analyzed for the presence of T. suis eggs. Six pens of 2 pigs each were used per treatment group. Add to Cart. SafeGuard AquaSol . Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days . Hematology and clinical chemistry parameters were evaluated in 24 chickens from each group. No further stirring during administration is necessary. Prepare a 1 to 1 dilution (pre-dilution) of Safe-Guard AquaSol in water: 1) Calculate the volume of Safe-Guard AquaSol to be administered daily. Chickens: Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1 mg/kg BW (0.454 mg/lb) for 5 consecutive days. Add to Cart-17% . RESIDUE WARNING: No withdrawal period is required when used according to labeling. Top 12 Sheep Breeds for Meat | Which One is Best for You? There were no abnormal post-treatment observations attributed to administration of FBZ at either study site. You can do it more than 2 times as a preventive measure, regardless if your chickens have worms or not. INDICATIONS: Chickens: Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens and for the treatment and control of adult A. galli and Heterakis gallinarum in breeding chickens and laying hens. In all three studies, the efficacy against A. galli (97.9%, 97.3%, and 93.9%) and H. gallinarum (99.8%, 96.9%, and 97.3%) was greater than 90%. Keep out of reach of children. Safe-Guard AquaSol 1 gallon Description Additional Information Documents Questions New Production Technology1 Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water Smaller particle size helps prevent sedimentation and clogged pipes, filters or nipple drinkers During treatment all chickens must have sole and unrestricted access to the medicated water. Once opened, do not store the container above 25C (77F). Formulated in France. Important: Always read and follow instructions provided by the manufacturer as concentration and dosage can change! For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). It may not display this or other websites correctly. The following formula should be used to estimate the dose: Total estimated body weight of the chickens in kilograms x 0.005 mL = amount of Safe-Guard Aquasol to use in milliliters in a day. Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a dailydose of 1.0 mg/kg BW (0.454 mg/lb) for 5 consecutive days. The SafeGuard Aquasol which costs about $280 last time I checked is the only one that works well in water. | What Drives Aggression and How to Avoid It. I read on this site 1/4 cc/ml per pound per bird, for 5 straight days, is that correct? Three dose confirmation studies were conducted in European Union (EU), using 105 Rhode Island Red breed hens (2 years old) for each study. The control group received non-medicated drinking water. The efficacy against adult A. galli was 100%. Aquasol is 200mg fenbendazole/ml of product (20%) -> recommendations from the product bulletin and the US National Lib. The large roundworm, Ascaridia galli is the most common intestinal parasite found in backyard and free range chicken flocks worldwide. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120chickens (60male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 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Last time I checked is the most common intestinal parasite found in backyard free! Inc., Rahway, NJ, USA and its affiliates 100 % chicken worldwide.